Saffron (its active constituent, crocin) supplementation attenuates lipid peroxidation and protects against tissue injury

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P68: Effects of Saffron Extract and its Active Constituent Crocin on Development of Neuropathic Pain in a Rat Model of Chronic Constriction Injury

Neuropathic pain is caused by a lesion or disease affecting the nervous systems, and is generally manifested as spontaneous pain, hyperalgesia, and allodynia. Previous study indicate that saffron has anti-inflammatory and antioxidant properties, we investigated whether saffron and crocin, a major constitute of saffron, would infleuence on behavioral responses of pain induced by chronic constric...

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Anti-obesity and Anorectic Effects of Saffron and its Constituent Crocin in Obese Wistar Rat

Background: Obesity is pandemic worldwide and a strong risk factor for cardio-metabolic disorders. The few approved anti-obesity drugs have poor efficacy and safety profile. Thus, there is an urgent need for new anti-obesity agents. According to the traditional medicine and a clinical trial, saffron may have anorexigenic and anti-obesity effects which need further investigation. Objectives: Ev...

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Evaluation of the Diuretic Effects of Crocin (active Constituent of Saffron) in Rats

Aim of this study is to confirm and investigate the diuretic effect of crocine which is the pharmacologically active component of Crocus sativus L. (saffron) and to study the possible mechanism of action in relation to urinary nitrite. Twenty four rats were divided into 3 groups; control, hydrochlorothiazide and crocine treated groups. Assay of the diuretic activity of crocine was performed by ...

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Evaluation of the Diuretic Effects of Crocin (active Constituent of Saffron) in Rats

Aim of this study is to confirm and investigate the diuretic effect of crocine which is the pharmacologically active component of Crocus sativus L. (saffron) and to study the possible mechanism of action in relation to urinary nitrite. Twenty four rats were divided into 3 groups; control, hydrochlorothiazide and crocine treated groups. Assay of the diuretic activity of crocine was performed by ...

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Protective effects of saffron extract and its active constituent crocin against oxidative stress and spatial learning and memory deficits induced by chronic stress in rats.

Although it is well established that chronic stress impairs spatial learning and memory, few studies have investigated possible ways to prevent its deleterious effects. Here, we investigated the effects of Crocus sativus L., commonly known as saffron, and its active constituent crocin on learning and memory loss and the induction of oxidative stress in the hippocampus by chronic stress. Rats we...

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ژورنال

عنوان ژورنال: Bratislava Medical Journal

سال: 2016

ISSN: 1336-0345

DOI: 10.4149/bll_2016_075